An Industry-leading Drug Discovery company who is searching for an Associate Director to join their Biomolecular Structure group. Their mission is to make a significant contribution to improving the quality of life and health across the globe, with core therapeutic areas including immuno-oncology, neurology, gastro-intestinal and other indications. You will have the opportunity to participate in pioneering science to enable drug discovery efforts, whilst working in state-of-the-art facilities.
Key Responsibilities:
Preparation and optimization of samples for cryo-EM
Expression, purification and characterization of membrane proteins
Data processing, automated pre-processing pipelines and reconstruction of high-resolution maps
Generation, optimization and analysis of cryo-EM grids and negative stain
Performing single particle cryo-EM on a range of targets
Requirements:
A PhD or equivalent in biochemistry/biophysics or related discipline
3+ years' industry experience in cryo-EM
Experience writing and manipulating scripts for handling and processing cryo-EM data
In depth practical experience in all aspects of structure determination workflow
Extensive knowledge of diverse software packages and their application to interpret cryo-EM image data
Experience with G Protein-Coupled Receptor (GPCR) is advantageous but not essential
Benefits:
Competitive salary compensation package including discretionary cash bonuses
25 days annual leave in addition to public holidays
Private Medical Insurance and a cash plan for dental and optical reimbursement
Income protection to cover long term absences due to ill health
Health and wellbeing benefits- including a subsidized individual gym membership
